Drug metabolism - cytochrome P450 - Reference pathway

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Reference pathway (KO) Reference pathway (EC) Reference pathway (Reaction) -----< Sort below by alphabet >----- Homo sapiens (human) Pan troglodytes (chimpanzee) Macaca mulatta (rhesus monkey) Mus musculus (mouse) Rattus norvegicus (rat) Canis familiaris (dog) Bos taurus (cow) Sus scrofa (pig) Equus caballus (horse) Monodelphis domestica (opossum) Ornithorhynchus anatinus (platypus) Gallus gallus (chicken) Xenopus laevis (African clawed frog) Xenopus tropicalis (western clawed frog) Danio rerio (zebrafish) Fugu rubripes (Japanese puffer fish) Tetraodon nigroviridis (green spotted puffer) Oryzias latipes (Japanese medaka) Ciona intestinalis (sea squirt) Strongylocentrotus purpuratus (purple sea urchin) Nematostella vectensis (sea anemone) Drosophila melanogaster (fruit fly) Drosophila pseudoobscura Drosophila ananassae Drosophila erecta Drosophila persimilis Drosophila sechellia Drosophila simulans Drosophila willistoni Drosophila yakuba Drosophila grimshawi Drosophila mojavensis Drosophila virilis Anopheles gambiae (mosquito) Aedes aegypti (yellow fever mosquito) Apis mellifera (honey bee) Bombyx mori (silkmoth) Tribolium castaneum (red flour beetle) Caenorhabditis elegans (nematode) Caenorhabditis briggsae Brugia malayi (filaria) Trichoplax adhaerens Arabidopsis thaliana (thale cress) Populus trichocarpa (black cottonwood) Vitis vinifera (wine grape) Oryza sativa japonica (Japanese rice) Physcomitrella patens subsp. patens Ostreococcus lucimarinus Ostreococcus tauri Chlamydomonas reinhardtii Cyanidioschyzon merolae Saccharomyces cerevisiae Saccharomyces paradoxus Saccharomyces mikatae Saccharomyces bayanus Ashbya gossypii (Eremothecium gossypii) Kluyveromyces lactis Kluyveromyces waltii Debaryomyces hansenii Pichia stipitis Vanderwaltozyma polyspora Candida glabrata Yarrowia lipolytica Schizosaccharomyces pombe Neurospora crassa Podospora anserina Magnaporthe grisea Fusarium graminearum Aspergillus nidulans Aspergillus fumigatus Aspergillus oryzae Aspergillus niger Neosartorya fischeri Sclerotinia sclerotiorum Botryotinia fuckeliana Cryptococcus neoformans JEC21 Cryptococcus neoformans B-3501A Phanerochaete chrysosporium Laccaria bicolor Ustilago maydis Malassezia globosa Monosiga brevicollis Giardia lamblia Dictyostelium discoideum Cryptosporidium parvum Cryptosporidium hominis Tetrahymena thermophila Paramecium tetraurelia Trypanosoma cruzi Leishmania major Entamoeba histolytica Thalassiosira pseudonana Escherichia coli K-12 MG1655 Escherichia coli K-12 W3110 Escherichia coli K-12 DH10B Escherichia coli O157 EDL933 (EHEC) Escherichia coli O157 Sakai (EHEC) Escherichia coli O157 EC4115 (EHEC) Escherichia coli CFT073 (UPEC) Escherichia coli UTI89 (UPEC) Escherichia coli 536 (UPEC) Escherichia coli APEC O1 Escherichia coli E24377A Escherichia coli HS Escherichia coli SECEC Escherichia coli SE11 Escherichia coli ATCC 8739 Salmonella enterica subsp. enterica serovar Typhi CT18 Salmonella enterica subsp. enterica serovar Typhi Ty2 Salmonella enterica subsp. enterica serovar Paratyphi A Salmonella enterica subsp. enterica serovar Paratyphi A AKU12601 Salmonella enterica subsp. enterica serovar Paratyphi B Salmonella enterica subsp. enterica serovar Choleraesuis Salmonella enterica subsp. enterica serovar Heidelberg Salmonella enterica subsp. enterica serovar Newport Salmonella enterica subsp. enterica serovar Schwarzengrund Salmonella enterica subsp. enterica serovar Agona Salmonella enterica subsp. enterica serovar Dublin Salmonella enterica subsp. enterica serovar Gallinarum Salmonella enterica subsp. enterica serovar Enteritidis Salmonella enterica subsp. arizonae Salmonella typhimurium LT2 Yersinia pestis CO92 Yersinia pestis KIM Yersinia pestis Mediaevails Yersinia pestis Antiqua Yersinia pestis Nepal516 Yersinia pestis Pestoides Yersinia pestis Angola Yersinia pseudotuberculosis IP32953 Yersinia pseudotuberculosis IP31758 Yersinia pseudotuberculosis YPIII Yersinia pseudotuberculosis PB1/+ Yersinia enterocolitica Shigella flexneri 301 (serotype 2a) Shigella flexneri 2457T (serotype 2a) Shigella flexneri 8401 (serotype 5b) Shigella sonnei Shigella boydii Sb227 Shigella boydii CDC 3083-94 Shigella dysenteriae Erwinia carotovora Erwinia tasmaniensis Photorhabdus luminescens Sodalis glossinidius Enterobacter sp. 638 Enterobacter sakazakii Klebsiella pneumoniae Klebsiella pneumoniae 342 Citrobacter koseri ATCC BAA-895 Serratia proteamaculans Proteus mirabilis Haemophilus influenzae Rd KW20 (serotype d) Pasteurella multocida Mannheimia succiniciproducens Actinobacillus pleuropneumoniae L20 (serotype 5b) Actinobacillus pleuropneumoniae JL03 (serotype 3) Actinobacillus pleuropneumoniae AP76 (serotype 7) Actinobacillus succinogenes Xylella fastidiosa 9a5c Xylella fastidiosa Temecula1 Xylella fastidiosa M12 Xylella fastidiosa M23 Xanthomonas campestris pv. campestris ATCC 33913 Xanthomonas campestris pv. campestris 8004 Xanthomonas campestris pv. campestris B100 Xanthomonas campestris pv. vesicatoria Xanthomonas axonopodis Xanthomonas oryzae KACC10331 Xanthomonas oryzae MAFF311018 Xanthomonas oryzae PXO99A Stenotrophomonas maltophilia Stenotrophomonas maltophilia R551-3 Vibrio cholerae O1 Vibrio cholerae O395 Vibrio vulnificus CMCP6 Vibrio vulnificus YJ016 Vibrio parahaemolyticus Vibrio fischeri Vibrio fischeri MJ11 Vibrio harveyi Photobacterium profundum Pseudomonas aeruginosa PAO1 Pseudomonas aeruginosa UCBPP-PA14 Pseudomonas aeruginosa PA7 Pseudomonas putida KT2440 Pseudomonas putida F1 Pseudomonas putida GB-1 Pseudomonas putida W619 Pseudomonas syringae pv. tomato DC3000 Pseudomonas syringae pv. syringae B728a Pseudomonas syringae pv. phaseolicola 1448A Pseudomonas fluorescens Pf-5 Pseudomonas fluorescens Pf0-1 Pseudomonas entomophila Pseudomonas mendocina Pseudomonas stutzeri Psychrobacter arcticum Psychrobacter cryohalolentis Psychrobacter sp. PRwf-1 Acinetobacter sp. ADP1 Acinetobacter baumannii ATCC 17978 Acinetobacter baumannii SDF Acinetobacter baumannii AYE Acinetobacter baumannii ACICU Shewanella oneidensis Shewanella denitrificans Shewanella frigidimarina Shewanella amazonensis Shewanella baltica OS155 Shewanella baltica OS185 Shewanella baltica OS195 Shewanella loihica Shewanella putrefaciens Shewanella sediminis Shewanella pealeana Shewanella sp. MR-4 Shewanella sp. MR-7 Shewanella sp. ANA-3 Shewanella sp. W3-18-1 Shewanella halifaxensis Shewanella woodyi ATCC51908 Idiomarina loihiensis Colwellia psychrerythraea Pseudoalteromonas haloplanktis Pseudoalteromonas atlantica Marinobacter aquaeolei Alteromonas macleodii Psychromonas ingrahamii Coxiella burnetii CbuG_Q212 Legionella pneumophila Philadelphia 1 Legionella pneumophila Lens Legionella pneumophila Paris Legionella pneumophila Corby Methylococcus capsulatus Thiomicrospira crunogena Nitrosococcus oceani Alkalilimnicola ehrlichei Halorhodospira halophila Hahella chejuensis Chromohalobacter salexigens Alcanivorax borkumensis Marinomonas sp. MWYL1 Aeromonas hydrophila Aeromonas salmonicida Acidithiobacillus ferrooxidans Neisseria meningitidis MC58 (serogroup B) Neisseria meningitidis Z2491 (serogroup A) Neisseria meningitidis FAM18 (serogroup C) Neisseria meningitidis 053442 (serogroup C) Neisseria gonorrhoeae Neisseria gonorrhoeae NCCP11945 Chromobacterium violaceum Ralstonia solanacearum Ralstonia pickettii Ralstonia eutropha JMP134 Ralstonia eutropha H16 Ralstonia metallidurans Cupriavidus taiwanensis Burkholderia mallei ATCC 23344 Burkholderia mallei SAVP1 Burkholderia mallei NCTC 10229 Burkholderia mallei NCTC 10247 Burkholderia xenovorans Burkholderia vietnamiensis Burkholderia sp. 383 Burkholderia cenocepacia AU1054 Burkholderia cenocepacia HI2424 Burkholderia cenocepacia MC0-3 Burkholderia cenocepacia J2315 Burkholderia cepacia Burkholderia ambifaria MC40-6 Burkholderia multivorans ATCC 17616 (JGI) Burkholderia multivorans ATCC 17616 (Tohoku) Burkholderia pseudomallei K96243 Burkholderia pseudomallei 1710b Burkholderia pseudomallei 1106a Burkholderia pseudomallei 668 Burkholderia thailandensis Burkholderia phymatum Burkholderia phytofirmans Bordetella pertussis Bordetella parapertussis Bordetella bronchiseptica Bordetella petrii Bordetella avium Rhodoferax ferrireducens Polaromonas sp. JS666 Polaromonas naphthalenivorans Acidovorax avenae Acidovorax sp. JS42 Verminephrobacter eiseniae Delftia acidovorans Methylibium petroleiphilum Herminiimonas arsenicoxydans Leptothrix cholodnii Nitrosomonas europaea Nitrosomonas eutropha Nitrosospira multiformis Azoarcus sp. EbN1 Azoarcus sp. BH72 Dechloromonas aromatica Thiobacillus denitrificans Methylobacillus flagellatus Campylobacter jejuni 81116 Arcobacter butzleri Geobacter sulfurreducens Geobacter metallireducens Geobacter uraniumreducens Geobacter lovleyi Geobacter bemidjiensis Pelobacter carbinolicus Pelobacter propionicus Desulfovibrio vulgaris Hildenborough Desulfovibrio vulgaris DP4 Desulfovibrio desulfuricans Bdellovibrio bacteriovorus Desulfotalea psychrophila Candidatus Desulfococcus oleovorans Anaeromyxobacter dehalogenans Anaeromyxobacter sp. Fw109-5 Anaeromyxobacter sp. K Myxococcus xanthus Sorangium cellulosum Syntrophus aciditrophicus Candidatus Pelagibacter ubique Mesorhizobium loti Mesorhizobium sp. BNC1 Parvibaculum lavamentivorans Sinorhizobium meliloti Sinorhizobium medicae Agrobacterium tumefaciens C58 (UWash/Dupont) Agrobacterium tumefaciens C58 (Cereon) Rhizobium etli CFN 42 Rhizobium etli CIAT 652 Rhizobium leguminosarum Rhizobium leguminosarum bv. trifolii WSM2304 Brucella melitensis 16M Brucella melitensis biovar Abortus Brucella abortus 9-941 Brucella abortus S19 Brucella suis 1330 Brucella suis ATCC 23445 Brucella ovis Brucella canis Ochrobactrum anthropi Bradyrhizobium japonicum Bradyrhizobium sp. ORS278 Bradyrhizobium sp. BTAi1 Rhodopseudomonas palustris CGA009 Rhodopseudomonas palustris HaA2 Rhodopseudomonas palustris BisB18 Rhodopseudomonas palustris BisB5 Rhodopseudomonas palustris BisA53 Rhodopseudomonas palustris TIE-1 Nitrobacter winogradskyi Nitrobacter hamburgensis Oligotropha carboxidovorans Bartonella henselae Bartonella quintana Bartonella bacilliformis Bartonella tribocorum Xanthobacter autotrophicus Azorhizobium caulinodans Methylobacterium extorquens Methylobacterium radiotolerans Methylobacterium sp. 4-46 Methylobacterium populi Beijerinckia indica Caulobacter crescentus Caulobacter sp. K31 Phenylobacterium zucineum Silicibacter pomeroyi Silicibacter sp. TM1040 Rhodobacter sphaeroides 2.4.1 Rhodobacter sphaeroides ATCC 17029 Rhodobacter sphaeroides ATCC 17025 Jannaschia sp. CCS1 Roseobacter denitrificans Paracoccus denitrificans Dinoroseobacter shibae Maricaulis maris Hyphomonas neptunium Zymomonas mobilis Novosphingobium aromaticivorans Sphingomonas wittichii Gluconobacter oxydans Granulobacter bethesdensis Acidiphilium cryptum JF-5 Gluconacetobacter diazotrophicus Rhodospirillum rubrum Rhodospirillum centenum Acidobacteria bacterium Solibacter usitatus Caldicellulosiruptor saccharolyticus Bacillus subtilis Bacillus halodurans Bacillus anthracis Ames Bacillus anthracis Ames 0581 Bacillus anthracis A2012 Bacillus anthracis Sterne Bacillus cereus ATCC 14579 Bacillus cereus ATCC 10987 Bacillus cereus ZK Bacillus cereus subsp. cytotoxis NVH 391-98 Bacillus thuringiensis 97-27 Bacillus thuringiensis Al Hakam Bacillus weihenstephanensis Bacillus licheniformis ATCC 14580 Bacillus licheniformis DSM13 Bacillus clausii Bacillus amyloliquefaciens Bacillus pumilus Oceanobacillus iheyensis Geobacillus kaustophilus Geobacillus thermodenitrificans Lysinibacillus sphaericus Exiguobacterium sibiricum Staphylococcus aureus N315 Staphylococcus aureus Mu50 Staphylococcus aureus Mu3 Staphylococcus aureus MW2 Staphylococcus aureus MRSA252 Staphylococcus aureus MSSA476 Staphylococcus aureus COL Staphylococcus aureus RF122 Staphylococcus aureus USA300 Staphylococcus aureus USA300 TCH1516 Staphylococcus aureus NCTC8325 Staphylococcus aureus JH9 Staphylococcus aureus JH1 Staphylococcus aureus Newman Staphylococcus epidermidis ATCC 12228 Staphylococcus epidermidis RP62A Staphylococcus haemolyticus Staphylococcus saprophyticus Listeria monocytogenes EGD-e Listeria monocytogenes F2365 Listeria innocua Listeria welshimeri SLCC5334 Lactococcus lactis subsp. lactis IL1403 Lactococcus lactis subsp. cremoris SK11 Lactococcus lactis subsp. cremoris MG1363 Streptococcus pyogenes SF370 (serotype M1) Streptococcus pyogenes MGAS5005 (serotype M1) Streptococcus pyogenes MGAS8232 (serotype M18) Streptococcus pyogenes MGAS315 (serotype M3) Streptococcus pyogenes SSI-1 (serotype M3) Streptococcus pyogenes MGAS10270 (serotype M3) Streptococcus pyogenes MGAS10750 (serotype M3) Streptococcus pyogenes MGAS2096 (serotype M3) Streptococcus pyogenes MGAS9429 (serotype M3) Streptococcus pyogenes Manfredo (serotype M5) Streptococcus pyogenes MGAS10394 (serotype M6) Streptococcus pyogenes MGAS6180 (serotype M28) Streptococcus pyogenes NZ131 (serotype M49) Streptococcus pneumoniae TIGR4 Streptococcus pneumoniae R6 Streptococcus pneumoniae D39 Streptococcus pneumoniae Hungary19A 6 Streptococcus pneumoniae CGSP14 Streptococcus pneumoniae G54 Streptococcus agalactiae 2603 (serotype V) Streptococcus agalactiae NEM316 (serotype III) Streptococcus agalactiae A909 (serotype Ia) Streptococcus mutans Streptococcus thermophilus CNRZ1066 Streptococcus thermophilus LMG18311 Streptococcus thermophilus LMD-9 Streptococcus sanguinis Streptococcus suis 05ZYH33 Streptococcus suis 98HAH33 Streptococcus gordonii Streptococcus equi Lactobacillus plantarum Lactobacillus johnsonii Lactobacillus acidophilus Lactobacillus sakei Lactobacillus salivarius Lactobacillus brevis Lactobacillus casei ATCC 334 Lactobacillus casei BL23 Lactobacillus gasseri Lactobacillus reuteri F275 (JGI) Lactobacillus reuteri F275 (Kitasato) Lactobacillus fermentum Enterococcus faecalis Oenococcus oeni Leuconostoc mesenteroides Leuconostoc citreum Symbiobacterium thermophilum Clostridium acetobutylicum Clostridium perfringens 13 Clostridium perfringens ATCC 13124 Clostridium perfringens SM101 Clostridium tetani E88 Clostridium thermocellum Clostridium difficile Clostridium botulinum A ATCC 3502 Clostridium botulinum A ATCC 19397 Clostridium botulinum A Hall Clostridium botulinum A3 Loch Maree Clostridium botulinum B Eklund 17B Clostridium botulinum B1 Okra Clostridium botulinum E3 Clostridium botulinum F Langeland Clostridium beijerinckii Clostridium kluyveri Clostridium phytofermentans Alkaliphilus metalliredigens Alkaliphilus oremlandii Carboxydothermus hydrogenoformans Desulfitobacterium hafniense Desulfotomaculum reducens Pelotomaculum thermopropionicum Candidatus Desulforudis audaxviator Finegoldia magna Thermoanaerobacter tengcongensis Thermoanaerobacter sp. X514 Thermoanaerobacter pseudethanolicus Moorella thermoacetica Natranaerobius thermophilus Coprothermobacter proteolyticus Mycoplasma penetrans Mycoplasma agalactiae Mycoplasma arthritidis Mycobacterium tuberculosis H37Rv Mycobacterium tuberculosis CDC1551 Mycobacterium tuberculosis H37Ra Mycobacterium tuberculosis F11 Mycobacterium bovis AF2122/97 Mycobacterium bovis BCG Pasteur 1173P2 Mycobacterium leprae Mycobacterium avium paratuberculosis Mycobacterium avium 104 Mycobacterium smegmatis Mycobacterium ulcerans Mycobacterium vanbaalenii Mycobacterium gilvum Mycobacterium abscessus ATCC 19977T Mycobacterium sp. MCS Mycobacterium sp. KMS Mycobacterium sp. JLS Mycobacterium marinum M Corynebacterium glutamicum ATCC 13032 (Kyowa Hakko) Corynebacterium glutamicum ATCC 13032 (Bielefeld) Corynebacterium glutamicum R Corynebacterium efficiens Corynebacterium diphtheriae Corynebacterium urealyticum Nocardia farcinica Rhodococcus sp. RHA1 Streptomyces coelicolor Streptomyces avermitilis Streptomyces griseus Tropheryma whipplei Twist Tropheryma whipplei TW08/27 Leifsonia xyli xyli CTCB07 Clavibacter michiganensis subsp. sepedonicus Arthrobacter aurescens Renibacterium salmoninarum Kocuria rhizophila Propionibacterium acnes Nocardioides sp. JS614 Thermobifida fusca Frankia sp. CcI3 Frankia sp. EAN1pec Frankia alni Acidothermus cellulolyticus Kineococcus radiotolerans Saccharopolyspora erythraea Salinispora tropica Salinispora arenicola Bifidobacterium longum NCC2705 Bifidobacterium longum DJO10A Bifidobacterium adolescentis Rubrobacter xylanophilus Rhodopirellula baltica Opitutus terrae Methylacidiphilum infernorum Akkermansia muciniphila Leptospira interrogans serovar lai Leptospira interrogans serovar Copenhageni Leptospira biflexa serovar Patoc Patoc 1 (Paris) Leptospira biflexa serovar Patoc Patoc 1 (Ames) Synechocystis sp. PCC6803 Synechococcus elongatus PCC6301 Synechococcus elongatus PCC7942 Synechococcus sp. CC9605 Synechococcus sp. CC9311 Synechococcus sp. WH7803 Synechococcus sp. PCC7002 Cyanobacteria Yellowstone A-Prime Cyanobacteria Yellowstone B-Prime Thermosynechococcus elongatus Microcystis aeruginosa Cyanothece sp. ATCC 51142 Gloeobacter violaceus Anabaena sp. PCC7120 Nostoc punctiforme Anabaena variabilis Prochlorococcus marinus AS9601 Prochlorococcus marinus MIT 9301 Trichodesmium erythraeum Acaryochloris marina Bacteroides fragilis YCH46 Bacteroides vulgatus Porphyromonas gingivalis ATCC 33277 Parabacteroides distasonis Salinibacter ruber Cytophaga hutchinsonii Gramella forsetii Flavobacterium johnsoniae Chlorobaculum tepidum Chlorobaculum parvum NCIB 8327 Chlorobium chlorochromatii Chlorobium phaeobacteroides DSM 266 Chlorobium phaeobacteroides BS1 Chlorobium limicola Prosthecochloris vibrioformis Pelodictyon phaeoclathratiforme Chloroherpeton thalassium Prosthecochloris aestuarii Roseiflexus sp. RS-1 Roseiflexus castenholzii DSM13941 Chloroflexus aurantiacus Herpetosiphon aurantiacus Elusimicrobium minutum Uncultured Termite group 1 bacterium phylotype Rs-D17 Deinococcus radiodurans Deinococcus geothermalis Thermus thermophilus HB27 Thermus thermophilus HB8 Aquifex aeolicus Hydrogenobaculum sp. Y04AAS1 Thermotoga maritima Thermotoga petrophila Thermotoga lettingae Thermotoga sp. RQ2 Thermosipho melanesiensis Fervidobacterium nodosum Petrotoga mobilis Dictyoglomus thermophilum Thermodesulfovibrio yellowstonii Methanococcus maripaludis S2 Methanosarcina acetivorans Methanosarcina barkeri Methanosarcina mazei Halobacterium sp. NRC-1 Halobacterium salinarum R1 Haloarcula marismortui Haloquadratum walsbyi Natronomonas pharaonis Thermoplasma acidophilum Thermoplasma volcanium Picrophilus torridus Pyrococcus horikoshii Pyrococcus furiosus Thermococcus kodakaraensis Thermococcus onnurineus Aeropyrum pernix Staphylothermus marinus Ignicoccus hospitalis Sulfolobus solfataricus Sulfolobus tokodaii Sulfolobus acidocaldarius Metallosphaera sedula Pyrobaculum aerophilum Pyrobaculum islandicum Pyrobaculum calidifontis Pyrobaculum arsenaticum Caldivirga maquilingensis Thermoproteus neutrophilus Thermofilum pendens Nitrosopumilus maritimus Candidatus Korarchaeum cryptofilum     Current selection