| Date | Map no | Title | Status |
|---|
| 2010-3-8 | 04962 | Vasopressin-regulated water reabsorption | Newly added |
| 2010-3-8 | 00532 | Glycosaminoglycan biosynthesis - chondroitin sulfate | Title changed |
| 2010-3-8 | 00534 | Glycosaminoglycan biosynthesis - heparan sulfate | Title changed |
| 2010-3-8 | 00533 | Glycosaminoglycan biosynthesis - keratan sulfate | Title changed |
| 2010-3-1 | 04626 | Plant-pathogen interaction | Newly added |
| 2010-2-4 | 04146 | Peroxisome | Newly added |
| 2010-1-28 | 00140 | Steroid hormone biosynthesis | Title changed; merging 00140 & 00150 |
| 2010-1-28 | 00150 | Androgen and estrogen metabolism | Deleted; merged into 00140 |
| 2010-1-25 | 04960 | Aldosterone-regulated sodium reabsorption | Newly added |
| 2010-1-6 | 00402 | Benzoxazinoid biosynthesis | Title changed |
| 2009-12-25 | 04672 | Intestinal immune network for IgA production | Newly added |
| 2009-12-10 | 04114 | Oocyte meiosis | Newly added |
| 2009-11-19 | 04623 | Cytosolic DNA-sensing pathway | Newly added |
| 2009-11-9 | 00440 | Phosphonate and phosphinate metabolism | Title changed |
| 2009-11-9 | 05416 | Viral myocarditis | Newly added |
| 2009-11-2 | 03040 | Spliceosome | Newly added |
| 2009-10-27 | 04621 | NOD-like receptor signaling pathway | Newly added |
| 2009-10-26 | 04113 | Meiosis - yeast | Newly added |
| 2009-10-13 | 05414 | Dilated cardiomyopathy | Newly added |
| 2009-9-16 | 04622 | RIG-I-like receptor signaling pathway | Newly added |
| 2009-9-11 | 03018 | RNA degradation | Newly added |
| 2009-9-7 | 05412 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) | Newly added |
| 2009-8-25 | 00945 | Stilbenoid, diarylheptanoid and gingerol biosynthesis | Newly added |
| 2009-8-25 | 00965 | Betalain biosynthesis | Newly added |
| 2009-8-24 | 05410 | Hypertrophic cardiomyopathy (HCM) | Newly added |
| 2009-8-24 | 04666 | Fc gamma R-mediated phagocytosis | Newly added |
| 2009-8-18 | 00901 | Indole alkaloid biosynthesis | Title changed |
| 2009-8-18 | 00950 | Isoquinoline alkaloid biosynthesis | Title changed |
| 2009-8-18 | 00960 | Tropane, piperidine and pyridine alkaloid biosynthesis | Title changed |
| 2009-8-11 | 00121 | Secondary bile acid biosynthesis | Newly added |
| 2009-8-11 | 00270 | Cysteine and methionine metabolism | New number; merging 00272 & 00271 |
| 2009-8-11 | 00272 | Cysteine metabolism | Deleted; merged into 00270 |
| 2009-8-11 | 00271 | Methionine metabolism | Deleted; merged into 00270 |
| 2009-8-7 | 00130 | Ubiquinone and other terpenoid-quinone biosynthesis | Title changed |
| 2009-7-27 | 04144 | Endocytosis | Newly added |
| 2009-7-27 | 00100 | Steroid biosynthesis | Title changed |
| 2009-7-27 | 00900 | Terpenoid backbone biosynthesis | Title changed |
| 2009-7-27 | 00909 | Sesquiterpenoid biosynthesis | Newly added |
| 2009-7-17 | 04722 | Neurotrophin signaling pathway | Newly added |
| 2009-7-17 | 05020 | Prion diseases | Newly added |
| 2009-7-14 | 00520 | Amino sugar and nucleotide sugar metabolism | Title changed |
| 2009-7-14 | 00530 | Aminosugars metabolism | Deleted; merged into 00520 |
| 2009-7-13 | 00250 | Alanine, aspartate and glutamate metabolism | New number; merging 00252 & 00251 |
| 2009-7-13 | 00252 | Alanine and aspartate metabolism | Deleted; merged into 00250 |
| 2009-7-13 | 00251 | Glutamate metabolism | Deleted; merged into 00250 |
| 2009-7-2 | 00120 | Primary bile acid biosynthesis | Title changed |
| 2009-7-2 | 04142 | Lysosome | Newly added |
| 2009-7-1 | 00220 | Urea cycle and metabolism of amino groups | Deleted; merged into 00330 |
| 2009-6-17 | 04062 | Chemokine signaling pathway | Newly added |
| 2009-6-15 | 03070 | Bacterial secretion system | Title changed; category changed |
| 2009-6-15 | 03080 | Type IV secretion system | Deleted; merged into 03070 |
| 2009-6-15 | 03090 | Type II secretion system | Deleted; merged into 03070 |
| 2009-6-8 | 04270 | Vascular smooth muscle contraction | Newly added |
| 2009-5-26 | 00966 | Glucosinolate biosynthesis | Newly added |
| 2009-5-13 | 04210 | Circadian rhythm - mammal | Title changed |
| 2009-5-13 | 04211 | Circadian rhythm - fly | Split from 04210 |
| 2009-5-13 | 04212 | Circadian rhythm - plant | Split from 04210 |
| 2009-5-8 | 00907 | Carotenoid biosynthesis, "Organism-specific" | Deleted; represented by 00906 |
| 2009-4-24 | 01100 | Metabolic pathways | Changed to global map |
| 2009-4-22 | 02011 | ABC transporters, "Organism-specific" | Deleted; represented by 02010 |
| 2009-4-21 | 04260 | Cardiac muscle contraction | Newly added |
| 2009-4-2 | 00031 | Inositol metabolism | Deleted; merged into 00562 |
| 2009-4-2 | 01030 | Glycan structures - biosynthesis 1 | Deleted; merged into 00510 |
| 2009-4-2 | 01031 | Glycan structures - biosynthesis 2 | Deleted; merged into 00510 |
| 2009-4-2 | 01032 | Glycan structures - degradation | Deleted; merged into 00511 |
| 2009-4-1 | 00511 | Other glycan degradation | Title changed |
| 2009-3-31 | 01330 | Signaling molecules and interaction | Deleted |
| 2009-3-31 | 01430 | Cell junctions | Deleted |
| 2009-3-31 | 01510 | Neurodegenerative diseases | Deleted |
| 2009-3-28 | 02021 | Two-component system, "Organism-specific" | Deleted; represented by 02020 |
| 2009-3-24 | 00130 | Ubiquinone and menaquinone biosynthesis | Title changed |
| 2009-3-23 | 05050 | Dentatorubropallidoluysian atrophy (DRPLA) | Deleted; represented by H00060 |
| 2009-3-23 | 05060 | Prion disease | Deleted; represented by H00061 |
| 2009-3-23 | 05016 | Huntington's disease | Newly added |
| 2009-3-23 | 05040 | Huntington's disease | Deleted |
| 2009-2-17 | 00602 | Glycosphingolipid biosynthesis - neo-lactoseries | Deleted; merged into 00601 |
| 2009-2-17 | 00601 | Glycosphingolipid biosynthesis - lacto and neolacto series | Title changed |
| 2009-2-16 | 05010 | Alzheimer's disease | Newly added |
| 2009-2-16 | 05010 | Alzheimer's disease | Deleted |
| 2008-12-23 | 01060 | Biosynthesis of plant secondary metabolites | Newly added |
| 2008-12-23 | 01061 | Biosynthesis of phenylpropanoids | Newly added |
| 2008-12-23 | 01062 | Biosynthesis of terpenoids and steroids | Newly added |
| 2008-12-23 | 01063 | Biosynthesis of alkaloids derived from shikimate pathway | Newly added |
| 2008-12-23 | 01064 | Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid | Newly added |
| 2008-12-23 | 01065 | Biosynthesis of alkaloids derived from histidine and purine | Newly added |
| 2008-12-23 | 01066 | Biosynthesis of alkaloids derived from terpenoid and polyketide | Newly added |
| 2008-12-23 | 01070 | Biosynthesis of plant hormones | Newly added |
| 2008-12-22 | 05014 | Amyotrophic lateral sclerosis (ALS) | Newly added |
| 2008-12-22 | 05030 | Amyotrophic lateral sclerosis (ALS) | Deleted |
| 2008-11-10 | 05012 | Parkinson's disease | Newly added |
| 2008-11-10 | 05020 | Parkinson's disease | Deleted |
| 2008-8-4 | 05322 | Systemic lupus erythematosus | Newly added |
| 2008-7-29 | 03450 | Non-homologous end-joining | Newly added |
| 2008-7-14 | 05340 | Primary immunodeficiency | Newly added |
| 2008-7-8 | 03440 | Homologous recombination | Newly added |
| 2008-7-7 | 05110 | Vibrio cholerae infection | Newly added |
| 2008-7-7 | 05111 | Vibrio cholerae pathogenic cycle | Newly added |
| 2008-7-7 | 05110 | Cholera - infection | Deleted |
| 2008-7-7 | 05111 | Cholera - colonization | Deleted |
| 2008-7-7 | 05112 | Cholera - diarrhea | Deleted |
| 2008-7-7 | 05113 | Cholera - environment | Deleted |
| 2008-7-7 | 05114 | Cholera - life cycle | Deleted |
| 2008-7-4 | 00982 | Drug metabolism - cytochrome P450 | Newly added |
| 2008-7-4 | 00983 | Drug metabolism - other enzymes | Newly added |
| 2008-6-23 | 05332 | Graft-versus-host disease | Newly added |
| 2008-6-5 | 03430 | Mismatch repair | Newly added |
| 2008-6-2 | 05330 | Allograft rejection | Newly added |
| 2008-5-28 | 03420 | Nucleotide excision repair | Newly added |
| 2008-5-14 | 03410 | Base excision repair | Newly added |
| 2008-4-28 | 05320 | Autoimmune thyroid disease | Newly added |
| 2008-4-22 | 00944 | Flavone and flavonol biosynthesis | Newly added |
| 2008-3-26 | 05200 | Pathways in cancer | Newly added |
| 2008-3-8 | 05310 | Asthma | Newly added |