Transferred or deleted entries

# Transferred entries (337 EC numbers)
# old EC number -> new EC number
1.1.1.68 -> 1.7.99.5
1.1.1.109 -> 1.3.1.28
1.1.1.171 -> 1.5.1.20
1.1.1.204 -> 1.17.1.4
1.1.1.242 -> 1.3.1.69
1.1.1.253 -> 1.5.1.33
1.1.2.1 -> 1.1.99.5
1.1.3.2 -> 1.13.12.4
1.1.3.22 -> 1.17.3.2
1.1.3.25 -> 1.1.99.18
1.1.3.26 -> 1.21.3.2
1.1.3.32 -> 1.14.21.1
1.1.3.33 -> 1.14.21.2
1.1.3.34 -> 1.14.21.3
1.1.3.35 -> 1.14.21.4
1.1.3.36 -> 1.14.21.5
1.1.99.15 -> 1.7.99.5
1.1.99.17 -> 1.1.5.2
1.2.1.14 -> 1.1.1.205
1.2.1.34 -> 1.1.1.131
1.2.1.35 -> 1.1.1.203
1.2.1.37 -> 1.1.1.204
1.2.1.55 -> 1.1.1.279
1.2.1.56 -> 1.1.1.280
1.2.3.2 -> 1.1.3.22
1.2.3.12 -> 1.14.13.82
1.2.99.1 -> 1.17.99.4
1.3.2.1 -> 1.3.99.2
1.3.2.2 -> 1.3.99.3
1.3.3.2 -> 1.14.21.6
1.3.99.9 -> 1.21.99.1
1.4.3.17 -> 1.3.3.10
1.4.4.1 -> 1.21.4.1
1.5.1.13 -> 1.17.1.5
1.5.3.9 -> 1.21.3.3
1.5.99.7 -> 1.5.8.2
1.5.99.10 -> 1.5.8.1
1.6.2.1 -> 1.6.99.3
1.6.4.1 -> 1.8.1.6
1.6.4.2 -> 1.8.1.7
1.6.4.3 -> 1.8.1.4
1.6.4.4 -> 1.8.1.8
1.6.4.5 -> 1.8.1.9
1.6.4.6 -> 1.8.1.10
1.6.4.7 -> 1.8.1.11
1.6.4.8 -> 1.8.1.12
1.6.4.9 -> 1.8.1.13
1.6.4.10 -> 1.8.1.14
1.6.6.1 -> 1.7.1.1
1.6.6.2 -> 1.7.1.2
1.6.6.3 -> 1.7.1.3
1.6.6.4 -> 1.7.1.4
1.6.6.5 -> 1.7.99.3
1.6.6.6 -> 1.7.1.5
1.6.6.7 -> 1.7.1.6
1.6.6.8 -> 1.7.1.7
1.6.6.10 -> 1.7.1.9
1.6.6.11 -> 1.7.1.10
1.6.6.12 -> 1.7.1.11
1.6.6.13 -> 1.7.1.12
1.6.7.1 -> 1.18.1.2
1.6.7.2 -> 1.18.1.1
1.6.8.1 -> 1.5.1.29
1.6.8.2 -> 1.5.1.30
1.6.99.2 -> 1.6.5.2
1.6.99.4 -> 1.18.1.2
1.6.99.7 -> 1.5.1.34
1.6.99.8 -> 1.16.1.3
1.6.99.9 -> 1.16.1.4
1.6.99.11 -> 1.16.1.5
1.6.99.12 -> 1.16.1.6
1.6.99.13 -> 1.16.1.7
1.7.99.3 -> 1.7.2.1
1.8.4.5 -> 1.8.4.13 and 1.8.4.14
1.8.4.6 -> 1.8.4.11
1.8.99.4 -> 1.8.4.8
1.9.3.2 -> 1.7.2.1
1.10.3.7 -> 1.21.3.4
1.10.3.8 -> 1.21.3.5
1.11.1.4 -> 1.13.11.11
1.12.1.1 -> 1.18.99.1
1.12.7.1 -> 1.18.99.1
1.12.99.1 -> 1.12.98.1
1.12.99.3 -> 1.12.5.1
1.12.99.4 -> 1.12.98.2
1.13.11.21 -> 1.14.99.36
1.13.99.2 -> 1.14.12.10
1.13.99.4 -> 1.14.12.9
1.13.99.5 -> 1.13.11.47
1.14.12.2 -> 1.14.13.35
1.14.12.6 -> 1.14.13.66
1.14.13.45 -> 1.14.18.2
1.14.99.5 -> 1.14.19.1
1.14.99.6 -> 1.14.19.2
1.14.99.13 -> 1.14.13.23
1.14.99.17 -> 1.14.16.5
1.14.99.25 -> 1.14.19.3
1.17.1.6 -> 1.17.99.5
1.18.3.1 -> 1.18.99.1
1.18.96.1 -> 1.15.1.2
1.18.99.1 -> 1.12.7.2
1.97.1.5 -> 1.20.4.1
1.97.1.6 -> 1.20.99.1
1.97.1.7 -> 1.20.4.2
2.1.1.135 -> 1.16.1.8
2.4.1.55 -> 2.7.8.14
2.4.1.72 -> 2.4.2.24
2.4.1.93 -> 4.2.2.18
2.4.1.124 -> 2.4.1.87
2.4.1.151 -> 2.4.1.87
2.4.1.169 -> 2.4.2.39
2.4.1.200 -> 4.2.2.17
2.4.1.204 -> 2.4.2.40
2.4.2.13 -> 2.5.1.6
2.5.1.37 -> 4.4.1.20
2.5.1.40 -> 4.2.3.9
2.6.1.53 -> 1.4.1.13
2.6.2.1 -> 2.1.4.1
2.7.1.37 -> 2.7.11.1, 2.7.11.8, 2.7.11.9, 2.7.11.10, 2.7.11.11, 2.7.11.12, 2.7.1.13, 2.7.11.21, 2.7.11.22, 2.7.11.24, 2.7.11.25, 2.7.11.30 and 2.7.12.1
2.7.1.38 -> 2.7.11.19
2.7.1.99 -> 2.7.11.2
2.7.1.104 -> 2.7.99.1
2.7.1.109 -> 2.7.11.31
2.7.1.110 -> 2.7.11.3
2.7.1.112 -> 2.7.10.1 and 2.7.10.2
2.7.1.115 -> 2.7.11.4
2.7.1.116 -> 2.7.11.5
2.7.1.117 -> 2.7.11.18
2.7.1.120 -> 2.7.11.17
2.7.1.123 -> 2.7.11.17
2.7.1.124 -> 2.7.11.6
2.7.1.125 -> 2.7.11.14
2.7.1.126 -> 2.7.11.15
2.7.1.128 -> 2.7.11.27
2.7.1.129 -> 2.7.11.7
2.7.1.131 -> 2.7.11.29
2.7.1.132 -> 2.7.11.28
2.7.1.135 -> 2.7.11.26
2.7.1.141 -> 2.7.11.23
2.7.1.152 -> 2.7.4.21
2.7.2.5 -> 6.3.4.16
2.7.2.9 -> 6.3.5.5
2.7.3.11 -> 2.7.13.1
2.7.3.12 -> 2.7.13.2
2.7.5.1 -> 5.4.2.2
2.7.5.2 -> 5.4.2.3
2.7.5.3 -> 5.4.2.1
2.7.5.4 -> 5.4.2.4
2.7.5.5 -> 5.4.2.5
2.7.5.6 -> 5.4.2.7
2.7.5.7 -> 5.4.2.8
2.7.7.16 -> 3.1.27.5
2.7.7.17 -> 3.1.27.1
2.7.7.26 -> 3.1.27.3
3.1.1.69 -> 3.5.1.89
3.1.2.24 -> 3.13.1.3
3.1.4.5 -> 3.1.21.1
3.1.4.6 -> 3.1.22.1
3.1.4.7 -> 3.1.31.1
3.1.4.8 -> 3.1.27.3
3.1.4.9 -> 3.1.30.2
3.1.4.10 -> 4.6.1.13
3.1.4.18 -> 3.1.16.1
3.1.4.19 -> 3.1.13.3
3.1.4.20 -> 3.1.13.1
3.1.4.21 -> 3.1.30.1
3.1.4.22 -> 3.1.27.5
3.1.4.23 -> 3.1.27.1
3.1.4.25 -> 3.1.11.1
3.1.4.27 -> 3.1.11.2
3.1.4.28 -> 3.1.11.3
3.1.4.30 -> 3.1.21.2
3.1.4.31 -> 3.1.11.4
3.1.4.47 -> 4.6.1.14
3.1.22.3 -> 3.1.21.7
3.1.25.2 -> 4.2.99.18
3.2.1.138 -> 4.2.2.15
3.2.3.1 -> 3.2.1.147
3.3.1.3 -> 3.2.1.148
3.3.2.3 -> 3.3.2.9 and 3.3.2.10
3.4.11.8 -> 3.4.19.3
3.4.13.1 -> 3.4.13.18
3.4.13.2 -> 3.4.13.18
3.4.13.6 -> 3.4.11.2
3.4.13.8 -> 3.4.13.18
3.4.13.10 -> 3.4.19.5
3.4.13.11 -> 3.4.13.18 and 3.4.13.19
3.4.13.13 -> 3.4.13.3
3.4.13.15 -> 3.4.13.18
3.4.14.3 -> 3.4.19.1
3.4.14.8 -> 3.4.14.9 and 3.4.14.10
3.4.15.2 -> 3.4.19.2
3.4.15.3 -> 3.4.15.5
3.4.16.1 -> 3.4.16.5 and 3.4.16.6
3.4.16.3 -> 3.4.16.5
3.4.17.7 -> 3.5.1.28
3.4.17.9 -> 3.4.17.4
3.4.19.8 -> 3.4.17.21
3.4.19.10 -> 3.5.1.28
3.4.21.8 -> 3.4.21.34 and 3.4.21.35
3.4.21.11 -> 3.4.21.36 and 3.4.21.37
3.4.21.13 -> 3.4.16.5 and 3.4.16.6
3.4.21.14 -> 3.4.21.62, 3.4.21.63, 3.4.21.64, 3.4.21.65 and 3.4.21.67
3.4.21.15 -> 3.4.21.63
3.4.21.28 -> 3.4.21.74
3.4.21.29 -> 3.4.21.74
3.4.21.30 -> 3.4.21.74
3.4.21.31 -> 3.4.21.68 and 3.4.21.73
3.4.21.44 -> 3.4.21.43
3.4.21.87 -> 3.4.23.49
3.4.22.4 -> 3.4.22.32 and 3.4.22.33
3.4.22.5 -> 3.4.22.33
3.4.22.9 -> 3.4.21.48
3.4.22.11 -> 3.4.24.56
3.4.22.12 -> 3.4.19.9
3.4.22.17 -> 3.4.22.52 and 3.4.22.53
3.4.22.18 -> 3.4.21.26
3.4.22.19 -> 3.4.24.15
3.4.22.21 -> 3.4.99.46
3.4.22.22 -> 3.4.24.37
3.4.22.23 -> 3.4.21.61
3.4.23.6 -> 3.4.23.18, 3.4.23.19, 3.4.23.20, 3.4.23.21, 3.4.23.22, 3.4.23.23, 3.4.23.24, 3.4.23.25, 3.4.23.26, 3.4.23.27, 3.4.23.28 and 3.4.23.30
3.4.23.7 -> 3.4.23.20
3.4.23.8 -> 3.4.23.25
3.4.23.9 -> 3.4.23.21
3.4.23.10 -> 3.4.23.22
3.4.23.27 -> 3.4.21.103
3.4.23.33 -> 3.4.21.101
3.4.23.37 -> 3.4.21.100
3.4.24.4 -> 3.4.24.25, 3.4.24.26, 3.4.24.27, 3.4.24.28, 3.4.24.29, 3.4.24.30, 3.4.24.31, 3.4.24.32, 3.4.24.39 and 3.4.24.40
3.4.24.8 -> 3.4.24.3
3.4.99.1 -> 3.4.23.28
3.4.99.4 -> 3.4.23.12
3.4.99.5 -> 3.4.24.3
3.4.99.6 -> 3.4.24.21
3.4.99.10 -> 3.4.24.56
3.4.99.13 -> 3.4.24.32
3.4.99.19 -> 3.4.23.15
3.4.99.22 -> 3.4.24.29
3.4.99.25 -> 3.4.23.21
3.4.99.26 -> 3.4.21.73 and 3.4.21.68
3.4.99.28 -> 3.4.21.60
3.4.99.30 -> 3.4.24.20
3.4.99.31 -> 3.4.24.15
3.4.99.32 -> 3.4.24.20
3.4.99.35 -> 3.4.23.36
3.4.99.36 -> 3.4.21.89
3.4.99.38 -> 3.4.23.17
3.4.99.41 -> 3.4.24.64
3.4.99.43 -> 3.4.23.42
3.4.99.44 -> 3.4.24.55
3.4.99.45 -> 3.4.24.56
3.4.99.46 -> 3.4.25.1
3.5.5.3 -> 4.3.99.1
3.6.1.32 -> 3.6.4.1
3.6.1.33 -> 3.6.4.2
3.6.1.34 -> 3.6.3.14
3.6.1.35 -> 3.6.3.6
3.6.1.36 -> 3.6.3.10
3.6.1.37 -> 3.6.3.9
3.6.1.38 -> 3.6.3.8
3.6.1.46 -> 3.6.5.1
3.6.1.47 -> 3.6.5.2
3.6.1.48 -> 3.6.5.3
3.6.1.49 -> 3.6.5.4
3.6.1.50 -> 3.6.5.5
3.6.1.51 -> 3.6.5.6
3.8.1.4 -> 1.97.1.10
3.8.2.1 -> 3.1.8.2
4.1.2.15 -> 2.5.1.54
4.1.2.16 -> 2.5.1.55
4.1.3.2 -> 2.3.3.9
4.1.3.5 -> 2.3.3.10
4.1.3.7 -> 2.3.3.1
4.1.3.8 -> 2.3.3.8
4.1.3.9 -> 2.3.3.11
4.1.3.10 -> 2.3.3.7
4.1.3.11 -> 2.3.3.12
4.1.3.12 -> 2.3.3.13
4.1.3.15 -> 2.2.1.5
4.1.3.18 -> 2.2.1.6
4.1.3.19 -> 2.5.1.56
4.1.3.20 -> 2.5.1.57
4.1.3.21 -> 2.3.3.14
4.1.3.23 -> 2.3.3.2
4.1.3.28 -> 2.3.3.3
4.1.3.29 -> 2.3.3.4
4.1.3.31 -> 2.3.3.5
4.1.3.33 -> 2.3.3.6
4.1.3.37 -> 2.2.1.7
4.1.99.4 -> 3.5.99.7
4.1.99.6 -> 4.2.3.6
4.1.99.7 -> 4.2.3.9
4.1.99.8 -> 4.2.3.14
4.1.99.9 -> 4.2.3.15
4.1.99.10 -> 4.2.3.16
4.2.1.13 -> 4.3.1.17
4.2.1.14 -> 4.3.1.18
4.2.1.16 -> 4.3.1.19
4.2.1.26 -> 4.3.1.9
4.2.1.29 -> 4.99.1.6
4.2.1.37 -> 3.3.2.4
4.2.1.38 -> 4.3.1.20
4.2.1.63 -> 3.3.2.3
4.2.1.64 -> 3.3.2.3
4.2.1.72 -> 4.1.1.78
4.2.1.102 -> 4.2.1.100
4.2.2.4 -> 4.2.2.20 and 4.2.2.21
4.2.99.1 -> 4.2.2.1
4.2.99.2 -> 4.2.3.1
4.2.99.3 -> 4.2.2.2
4.2.99.4 -> 4.2.2.3
4.2.99.7 -> 4.2.3.2
4.2.99.8 -> 2.5.1.47
4.2.99.9 -> 2.5.1.48
4.2.99.10 -> 2.5.1.49
4.2.99.11 -> 4.2.3.3
4.2.99.13 -> 2.5.1.50
4.2.99.14 -> 2.5.1.51
4.2.99.15 -> 2.5.1.52
4.2.99.16 -> 2.5.1.53
4.2.99.19 -> 4.4.1.23
4.3.1.8 -> 2.5.1.61
4.3.99.1 -> 4.2.1.104
4.4.1.18 -> 1.8.3.5
4.6.1.3 -> 4.2.3.4
4.6.1.4 -> 4.2.3.5
4.6.1.5 -> 4.2.3.7
4.6.1.7 -> 4.2.3.8
4.6.1.8 -> 4.2.3.10
4.6.1.9 -> 4.2.3.11
4.6.1.10 -> 4.2.3.12
4.6.1.11 -> 4.2.3.13
5.3.1.10 -> 3.5.99.6
5.3.1.19 -> 2.6.1.16
5.4.99.6 -> 5.4.4.2
6.3.1.3 -> 6.3.4.13

# Deleted entries (230 EC numbers)
1.1.1.70: D-glucuronolactone dehydrogenase. Now included with EC 1.2.1.3 aldehyde dehydrogenase (NAD+) (EC 1.1.1.70 created 1965, deleted 1978)
1.1.1.74: D-aminopropanol dehydrogenase (reaction due to EC 1.1.1.4 (R,R)-butanediol dehydrogenase) (EC 1.1.1.74 created 1972, deleted 1976)
1.1.1.89: dihydroxyisovalerate dehydrogenase (isomerizing). Now included with EC 1.1.1.86 ketol-acid reductoisomerase (EC 1.1.1.89 created 1972, deleted 1976)
1.1.1.139: - polyol dehydrogenase (NADP+). Now included with EC 1.1.1.21 aldehyde reductase (EC 1.1.1.139 created 1972, deleted 1978)
1.1.1.155: the enzyme is identical to EC 1.1.1.87, homoisocitrate dehydrogenase (EC 1.1.1.155 created 1976, deleted 2004)
1.1.1.180: mannonate dehydrogenase (NAD(P)+). Now included with EC 1.1.1.131 mannuronate reductase] (EC 1.1.1.180 created 1983, deleted 1984)
1.1.1.182: fenchol dehydrogenase. Now included with EC 1.1.1.198 (+)-borneol dehydrogenase, EC 1.1.1.227 (-)-borneol dehydrogenase and EC 1.1.1.228 (+)-sabinol dehydrogenase (EC 1.1.1.182 created 1983, deleted 1990)
1.1.1.249: provisional entry deleted. Revised and reinstated as EC 2.5.1.46 deoxyhypusine synthase. (EC 1.1.1.249 provisional version created 1999, deleted 1999 [reinstated 2001 as EC 2.5.1.46])
1.1.3.1: glycolate oxidase. Now included with EC 1.1.3.15 (S)-2-hydroxy-acid oxidase (EC 1.1.3.1 created 1961, deleted 1984)
1.1.3.31: methanol oxidase. Cannot be distinguished from EC 1.1.3.13, alcohol oxidase. (EC 1.1.3.31 created 1992, deleted 2003)
1.1.5.1: cellobiose dehydrogenase (quinone). Now known to be proteolytic product of EC 1.1.99.18, cellobiose dehydrogenase (acceptor). (EC 1.1.5.1 created 1983, deleted 2002)
1.1.99.19: uracil dehydrogenase. Now EC 1.17.99.4, uracil/thymine dehydrogenase (EC 1.1.99.19 created 1961 as EC 1.2.99.1, transferred 1984 to EC 1.1.99.19, deleted 2006)
1.2.1.1: glutathione-dependent formaldehyde dehydrogenase. This enzyme was classified on the basis of an incorrect reaction. It has been replaced by two enzymes, EC 1.1.1.284, S-(hydroxymethyl)glutathione dehydrogenase and EC 4.4.1.22, S-(hydroxymethyl)glutathione synthase (EC 1.2.1.1 created 1961, modified 1982, modified 2002, deleted 2005)
1.2.1.6: benzaldehyde dehydrogenase (EC 1.2.1.6 created 1961, deleted 1965)
1.2.3.10: carbon-monoxide oxidase. Activity due to EC 1.2.2.4 carbon-monoxide oxygenase (cytochrome b-561). (EC 1.2.3.10 created 1990, deleted 2003)
1.2.4.3: 2-oxoisocaproate dehydrogenase. Now included with EC 1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (lipoamide) (EC 1.2.4.3 created 1972, deleted 1978)
1.2.7.9: This enzyme is identical to EC 1.2.7.3, 2-oxoglutarate synthase (EC 1.2.7.9 created 2003, deleted 2005)
1.3.1.23: cholestenone beta-reductase. The enzyme is identical to EC 1.3.1.3, delta4-3-oxosteroid 5beta-reductase. (EC 1.3.1.23 created 1972, deleted 2005)
1.3.1.50: tetrahydroxynaphthalene reductase. Now EC 1.1.1.252 tetrahydroxynaphthalene reductase (EC 1.3.1.50 created 1992, deleted 1999)
1.3.1.55: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase. Enzyme is identical to EC 1.3.1.25, 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase (EC 1.3.1.55 created 1999, deleted 2004)
1.3.1.59: 1,2-dihydroxy-3-methyl-1,2-dihydrobenzoate dehydrogenase. No evidence the paper cited that the enzyme exists (EC 1.3.1.59 created 2000, deleted 2006)
1.4.1.6: now included with EC 1.4.4.1 D-proline reductase (dithiol) (EC 1.4.1.6 created 1961, deleted 1982)
1.4.1.22: ornithine cyclodeaminase. It was pointed out during the public-review process that there is no overall consumption of NAD+ during the reaction. As a result, transfer of the enzyme from EC 4.3.1.12 was not necessary and EC 1.4.1.22 was withdrawn before being made official. (EC 1.4.1.22 created 2006, deleted 2006)
1.4.3.9: tyramine oxidase. Now included with EC 1.4.3.4 amine oxidase (flavin-containing) (EC 1.4.3.9 created 1972, deleted 1984)
1.4.3.18: Not approved as the enzyme was shown to be a dehydrogenase and not an oxidase (see EC 1.5.99.12 cytokinin dehydrogenase). (EC 1.4.3.18 proposed 2000)
1.5.1.4: dihydrofolate dehydrogenase. Now included with EC 1.5.1.3 dihydrofolate reductase (EC 1.5.1.4 created 1961, deleted 1976)
1.5.1.14: 1,2-didehydropipecolate reductase. Now included with EC 1.5.1.21 delta1-piperideine-2-carboxylate reductase (EC 1.5.1.14 created 1976, deleted 1989)
1.5.3.3: spermine oxidase (EC 1.5.3.3 created 1961, deleted 1972)
1.5.3.8: now included with EC 1.3.3.8 tetrahydroberberine oxidase (EC 1.5.3.8 created 1989, deleted 1992)
1.6.2.3: cytochrome reductase (NADPH) (EC 1.6.2.3 created 1972, deleted 1965)
1.6.5.1: quinone reductase (EC 1.6.5.1 created 1961, deleted 1965)
1.7.1.8: withdrawn in the light of further information on the acceptor (EC 1.7.1.8 created 2002, deleted 2002)
1.7.99.2: nitric-oxide reductase. Reaction may have been due to the combined action of EC 1.7.99.6 nitrous-oxide reductase and EC 1.7.99.7 nitric-oxide reductase (EC 1.7.99.2 created 1961, modified 1976, deleted 1992)
1.7.99.5: 5,10-methylenetetrahydrofolate reductase (FADH2). Now included with EC 1.5.1.20">1.5.1.20, methylenetetrahydrofolate reductase [NAD(P)H]. Based on the reference, it had been thought that this was a separate enzyme from EC 1.5.1.20 but the reference upon which the entry was based has since been disproved. (EC 1.7.99.5 created 1965 as EC 1.1.1.68, transferred 1978 to EC 1.1.99.15, transferred 1980 to EC 1.7.99.5, deleted 2005)
1.8.1.1: cysteamine dehydrogenase (EC 1.8.1.1 created 1961, deleted 1972)
1.8.6.1: Nitrate-ester reductase. Now included with EC 2.5.1.18 glutathione transferase (EC 1.8.6.1 created 1961, deleted 1976)
1.12.99.2: coenzyme-M-7-mercaptoheptanoylthreonine-phosphate-heterodisulfide hydrogenase. Now shown to be two enzymes, EC 1.12.98.3, Methanosarcina-phenazine hydrogenase and EC 1.8.98.1, CoB—CoM heterodisulfide reductase. (EC 1.12.99.2 created 1992, deleted 2002)
1.12.99.5: 3,4-dihydroxyquinoline 2,4-dioxygenase. Identical to EC 1.13.11.47 (EC 1.12.99.5 created 1999, deleted 2001)
1.13.11.7: 3,4-dihydroxyphenylacetate 3,4-dioxygenase (EC 1.13.11.7 created 1965 as EC 1.13.1.7, transferred 1972 to EC 1.13.11.7, deleted 1980)
1.13.11.42: indoleamine-pyrrole 2,3-dioxygenase (EC 1.13.11.42 created 1992, deleted 2006)
1.13.12.10: lysine 6-monooxygenase. reaction covered by EC 1.14.13.59, L-lysine 6-monooxygenase (NADPH) (EC 1.13.12.10 created 1989, modified 1999, deleted 2001)
1.13.12.11: methylphenyltetrahydropyridine N-monooxygenase. The activity is due to EC 1.14.13.8, flavin-containing monooxygenase. (EC 1.13.12.11 created 1992, deleted 2006)
1.14.11.5: 5-hydroxymethyluracil,2-oxoglutarate dioxygenase. Now included with EC 1.14.11.6 thymine dioxygenase (EC 1.14.11.5 created 1972, deleted 1976)
1.14.13.65: 2-hydroxyquinoline 8-monooxygenase (EC 1.14.13.65 created 1999, deleted 2006)
1.14.14.2: benzopyrene 3-monooxygenase. Now included with EC 1.14.14.1 unspecific monooxygenase (EC 1.14.14.2 created 1972, deleted 1976)
1.14.14.4: choline monooxygenase. Identical to EC 1.14.15.7 (EC 1.14.14.4 created 2000, deleted 2002)
1.14.17.2: 4-coumarate 3-monooxygenase. Now included with EC 1.14.18.1 monophenol monooxygenase (EC 1.14.17.2 created 1972, deleted 1984)
1.14.99.8: arene monooxygenase (epoxidizing). Now included with EC 1.14.14.1 unspecific monooxygenase (EC 1.14.99.8 created 1972, deleted 1984)
1.14.99.16: methylsterol monooxygenase, transferred to EC 1.14.13.72 (EC 1.14.99.16 created 1972, deleted 2002)
1.14.99.18: CMP-N-acetylneuraminate monooxygenase. (EC 1.14.99.18 created 1976, modified 1999, deleted 2003)
2.1.1.23: protein-arginine N-methyltransferase. Now listed as EC 2.1.1.124 [cytochrome c]-arginine N-methyltransferase, EC 2.1.1.125 histone-arginine N-methyltransferase and EC 2.1.1.126 [myelin basic protein]-arginine N-methyltransferase. (EC 2.1.1.23 created 1972, modified 1976, modified 1983, deleted 1999)
2.1.1.24: protein-gamma-glutamate O-methyltransferase. Now listed as EC 2.1.1.77 protein-L-isoaspartate(D-aspartate) O-methyltransferase, EC 2.1.1.80 protein-glutamate O-methyltransferase and EC 2.1.1.100 protein-S-isoprenylcysteine O-methyltransferase. (EC 2.1.1.24 created 1972, modified 1983, modified 1989, deleted 1992)
2.1.1.30: tRNA (purine-2- or -6-)-methyltransferase. Reactions previously described are due to EC 2.1.1.32 tRNA (guanine-N2-)-methyltransferase. (EC 2.1.1.30 created 1972, deleted 1981)
2.1.1.58: mRNA (adenosine-2'-O-)-methyltransferase. Now included with EC 2.1.1.57 mRNA (nucleoside-2'-O-)-methyltransferase. (EC 2.1.1.58 created 1981, deleted 1984)
2.1.1.73: site-specific DNA-methyltransferase (cytosine-specific). Reaction is that of EC 2.1.1.37, DNA (cytosine-5-)-methyltransferase. (EC 2.1.1.73 created 1984, deleted 2003)
2.1.1.81: nicotine N-methyltransferase. Now included with EC 2.1.1.49 amine N-methyltransferase. (EC 2.1.1.81 created 1989, deleted 1990)
2.1.1.134: myo-inositol 6-O-methyltransferase. Now included with EC 2.1.1.129, inositol 4-methyltransferase (EC 2.1.1.134 created 1999, deleted 2002)
2.1.1.138: methylarsonite methyltransferase. Reaction due to EC 2.1.1.137, methylarsonite methyltransferase. (EC 2.1.1.138 created 2000, deleted 2003)
2.1.2.6: glutamate formyltransferase. Now included with EC 2.1.2.5 glutamate formiminotransferase. (EC 2.1.2.6 created 1965, deleted 1984)
2.1.2.12: now EC 2.1.1.74 methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) (EC 2.1.2.12 created 1983, deleted 1984)
2.1.3.4: malonyl-CoA carboxyltransferase. (EC 2.1.3.4 created 1965, deleted 1972)
2.3.1.55: kanamycin 6'-N-acetyltransferase identical to EC 2.3.1.82 aminoglycoside N6'-acetyltransferase (EC 2.3.1.55 created 1976, deleted 1999)
2.3.1.120: 6'-deoxychalcone synthase. The reaction listed is due to EC 2.3.1.74 naringenin-chalcone synthase (EC 2.3.1.120 created 1990, deleted 1992)
2.3.1.124: already listed as EC 2.3.1.20 diacylglycerol O-acyltransferase (EC 2.3.1.124 created 1990, deleted 1992)
2.4.1.3: amylomaltase. Now included with EC 2.4.1.25, 4-alpha-glucanotransferase (EC 2.4.1.3 created 1961, deleted 1972)
2.4.1.6: maltose 3-glycosyltransferase (EC 2.4.1.6 created 1961, deleted 1972)
2.4.1.42: UDP-glucuronate—estriol 17beta-D-glucuronosyltransferase. Now included with EC 2.4.1.17 UDP-glucuronosyltransferase (EC 2.4.1.42 created 1972, deleted 1984)
2.4.1.51: UDP-N-acetylglucosamine—glycoprotein N-acetylglucosaminyltransferase. Now listed as EC 2.4.1.101 (alpha-1,3-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase), EC 2.4.1.143 (alpha-1,6-mannosyl-glycoprotein beta-1,2-N-acetylglucosaminyltransferase), EC 2.4.1.144 (beta-1,4-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase) and EC 2.4.1.145 (alpha-1,3-mannosyl-glycoprotein beta-1,4-N-acetylglucosaminyltransferase) (EC 2.4.1.51 created 1972, deleted 1984)
2.4.1.59: UDP-glucuronate—estradiol glucuronosyltransferase. Now included with EC 2.4.1.17 UDP-glucuronosyltransferase (EC 2.4.1.59 created 1972, deleted 1984)
2.4.1.61: UDP-glucuronate—estriol 16alpha-glucuronosyltransferase. Now included with EC 2.4.1.17 UDP-glucuronosyltransferase (EC 2.4.1.61 created 1972, deleted 1984)
2.4.1.75: insufficient evidence to conclude that this is a different enzyme from EC 2.4.1.43, polygalacturonate 4-alpha-galacturonosyltransferase (EC 2.4.1.75 created 1976, deleted 2005)
2.4.1.76: UDP-glucuronate—bilirubin glucuronosyltransferase. Now included with EC 2.4.1.17, UDP-glucuronosyltransferase (EC 2.4.1.76 created 1976, deleted 1984)
2.4.1.77: UDP-glucuronate—bilirubin-glucuronoside glucuronosyltransferase. Now included with EC 2.4.1.17, UDP-glucuronosyltransferase (EC 2.4.1.77 created 1976, deleted 1984)
2.4.1.84: UDP-glucuronate—1,2-diacylglycerol glucuronosyltransferase. Now included with EC 2.4.1.17, UDP-glucuronosyltransferase (EC 2.4.1.84 created 1976, deleted 1984)
2.4.1.89: Galactosylglucosaminylgalactosylglucosylceramide alpha-L-fucosyltransferase - now included with EC 2.4.1.69 galactoside 2-L-fucosyltransferase (EC 2.4.1.89 created 1976, deleted 1984)
2.4.1.98: UDP-galactose—N-acetylglucosamine beta-D-galactosyl-transferase. Now included with EC 2.4.1.90, N-acetyllactosamine synthase (EC 2.4.1.98 created 1980, deleted 1984)
2.4.1.107: UDP-glucuronate—testosterone glucuronosyltransferase. Now included with EC 2.4.1.17, UDP-glucuronosyltransferase (EC 2.4.1.107 created 1983, deleted 1984)
2.4.1.108: UDP-glucuronate—phenol glucuronosyltransferase. Now included with EC 2.4.1.17, UDP-glucuronosyltransferase (EC 2.4.1.108 created 1983, deleted 1984)
2.4.1.154: globotriosylceramide beta-1,6-N-acetylgalactosaminyl-transferase. The enzyme is identical to EC 2.4.1.79, globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase. The reference cited referred to a 1->3 linkage and not to a 1->6 linkage, as indicated in the enzyme entry. (EC 2.4.1.154 created 1986, deleted 2006)
2.4.1.233: anthocyanidin 3-O-glucosyltransferase. The enzyme is identical to EC 2.4.1.115, anthocyanidin 3-O-glucosyltransferase (EC 2.4.1.233 created 2004, deleted 2005)
2.4.1.235: Enzyme is identical to EC 2.4.1.116, cyanidin 3-O-rutinoside 5-O-glucosyltransferase (EC 2.4.1.235 created 2004, deleted 2006)
2.5.1.12: glutathione S-alkyltransferase. Now included with EC 2.5.1.18 glutathione transferase (EC 2.5.1.12 created 1972, deleted 1976)
2.5.1.13: glutathione S-aryltransferase. Now included with EC 2.5.1.18 glutathione transferase (EC 2.5.1.13 created 1972, deleted 1976)
2.5.1.14: glutathione S-aralkyltransferase. Now included with EC 2.5.1.18 glutathione transferase (EC 2.5.1.14 created 1972, deleted 1976)
2.6.1.10: D-aspartate transaminase. Now included with EC 2.6.1.21 D-alanine transaminase (EC 2.6.1.10 created 1961, deleted 1972)
2.6.1.20: tyrosine—pyruvate transaminase (EC 2.6.1.20 created 1965, deleted 1972)
2.6.1.25: thyroxine transaminase. Now included with EC 2.6.1.24 diiodotyrosine transaminase (EC 2.6.1.25 created 1972, deleted 1984)
2.6.1.61: (R)-3-amino-2-methylpropionate transaminase. Enzyme is identical to EC 2.6.1.40, (R)-3-amino-2-methylpropionate—pyruvate transaminase (EC 2.6.1.61 created 1982, deleted 2004)
2.6.1.69: N2-acetylornithine 5-transaminase. Enzyme is identical to EC 2.6.1.11, acetylornithine transaminase (EC 2.6.1.69 created 1989, deleted 2004)
2.7.1.9: acetylaminodeoxyglucose kinase (EC 2.7.1.9 created 1961, deleted 1965)
2.7.1.57: mannitol kinase (EC 2.7.1.57 created 1972, deleted 1984)
2.7.1.70: protamine kinase. This enzyme is not dependent on cAMP as was thought and is therefore identical to EC 2.7.1.37, protein kinase. (EC 2.7.1.70 created 1972, deleted 2004)
2.7.1.75: thymidine kinase. Now EC 2.7.1.21 thymidine kinase (EC 2.7.1.75 created 1972, deleted 1976)
2.7.1.96: NADH kinase. Now included with EC 2.7.1.86 NADH kinase (EC 2.7.1.96 created 1978, deleted 1978)
2.7.1.97: identical with EC 2.7.1.125 rhodopsin kinase (EC 2.7.1.97 created 1978, deleted 1992)
2.7.1.98: phosphoenolpyruvate—fructose phosphotransferase (EC 2.7.1.98 created 1978, deleted 1984)
2.7.1.111: Now listed as EC 2.7.1.128 [acetyl-CoA carboxylase] kinase (EC 2.7.1.111 created 1984, deleted 1992)
2.7.1.133: inositol-trisphosphate 6-kinase. Now included with EC 2.7.1.134, inositol-tetrakisphosphate 1-kinase (EC 2.7.1.133 created 1990, deleted 2002)
2.7.1.139: inositol-trisphosphate 5-kinase. Now included with EC 2.7.1.134, inositol-tetrakisphosphate 1-kinase (EC 2.7.1.139 created 1992, deleted 2002)
2.7.4.5: deoxycytidylate kinase. Now included with EC 2.7.4.14 cytidylate kinase (EC 2.7.4.5 created 1961, deleted 1972)
2.7.7.20: This entry was identical with EC 2.7.7.25 tRNA adenylyltransferase (EC 2.7.7.20 created 1965, deleted 1972)
2.7.7.29: hexose-1-phosphate guanylyltransferase. Enzyme is not specific for GTP and therefore is identical to EC 2.7.7.28, nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase (EC 2.7.7.29 created 1972, deleted 2004)
2.7.8.16: 1-alkyl-2-acetylglycerol choline phosphotransferase. Now included with EC 2.7.8.2 diacylglycerol cholinephosphotransferase (EC 2.7.8.16 created 1983, deleted 1986)
2.8.2.12: heparitin sulfotransferase. Enzyme identical to EC 2.8.2.8, [heparan sulfate]-glucosamine N-sulfotransferase (EC 2.8.2.12 created 1972, deleted 2001)
2.8.3.4: butyrate CoA-transferase (EC 2.8.3.4 created 1961, deleted 1964)
3.1.1.9: benzoylcholinesterase; a side reaction of EC 3.1.1.8 cholinesterase (EC 3.1.1.9 created 1961, deleted 1972)
3.1.1.12: vitamin A esterase, now believed to be identical with EC 3.1.1.1 carboxylesterase (EC 3.1.1.12 created 1961, deleted 1972)
3.1.1.16: 4-carboxymethyl-4-hydroxyisocrotonolactonase. This reaction was due to a mixture of EC 5.3.3.4 (muconolactone D-isomerase) and EC 3.1.1.24 (3-oxoadipate enol-lactonase) (EC 3.1.1.16 created 1961, deleted 1972)
3.1.1.18: aldonolactonase. Now included with EC 3.1.1.17 gluconolactonase (EC 3.1.1.18 created 1961, deleted 1982)
3.1.1.62: Now listed as EC 3.5.1.47 N-acetyldiaminopimelate deacetylase (EC 3.1.1.62 created 1989, deleted 1992)
3.1.2.8: S-acetoacylglutathione hydrolase. Now included with EC 3.1.2.6 hydroxyacylglutathione hydrolase (EC 3.1.2.8 created 1961, deleted 1978)
3.1.2.9: S-acetoacetylhydrolipoate hydrolase (EC 3.1.2.9 created 1961, deleted 1964)
3.1.3.30: 3'-phosphoadenylylsulfate 3'-phosphatase. Now included with EC 3.1.3.7 3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.30 created 1972, deleted 1992)
3.1.3.61: inositol-1,4,5-trisphosphate 1-phosphatase, as its existence has not been established (EC 3.1.3.61 created 1992, deleted 2002)
3.1.3.65: inositol-1,3-bisphosphate 3-phosphatase. Now included with EC 3.1.3.64, phosphatidylinositol-3-phosphatase(EC 3.1.3.65 created 1992, deleted 2002)
3.1.4.24: endoribonuclease III (EC 3.1.4.24 created 1972, deleted 1978)
3.1.4.26: exodeoxyribonuclease II (EC 3.1.4.26 created 1972, deleted 1978)
3.1.4.29: oligodeoxyribonucleate exonuclease (EC 3.1.4.29 created 1972, deleted 1978)
3.1.4.32: endodeoxyribonuclease (ATP- and S-adenosylmethionine-dependent). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease (EC 3.1.4.32 created 1972, deleted 1978)
3.1.4.33: endodeoxyribonuclease (ATP-hydrolysing). See EC 3.1.21.3 type 1 site-specific deoxyribonuclease and EC 3.1.21.5 type III site-specific deoxyribonuclease (EC 3.1.4.33 created 1972, deleted 1978)
3.1.4.34: hybrid nuclease. See subclasses EC 3.1.15, EC 3.1.16, EC 3.1.30 and EC 3.1.31 (EC 3.1.4.34 created 1972, deleted 1978)
3.1.4.36: 1,2-cyclic-inositol-phosphate phosphodiesterase. Now included with EC 3.1.4.43, glycerophosphoinositol inositolphosphodiesterase (EC 3.1.4.36 created 1976, deleted 2002)
3.1.6.5: sinigrin sulfohydrolase; myrosulfatase (EC 3.1.6.5 created 1961, deleted 1964)
3.2.1.5: licheninase (EC 3.2.1.5 created 1961, deleted 1964)
3.2.1.9: amylopectin-1,6-glucosidase (EC 3.2.1.9 created 1961, deleted 1972)
3.2.1.12: cycloheptaglucanase. Now included with EC 3.2.1.54 cyclomaltodextrinase (EC 3.2.1.12 created 1961, deleted 1976)
3.2.1.13: cyclohexaglucanase. Now included with EC 3.2.1.54 cyclomaltodextrinase (EC 3.2.1.13 created 1961, deleted 1976)
3.2.1.16: alginase (EC 3.2.1.16 created 1961, deleted 1972)
3.2.1.19: heparinase (EC 3.2.1.19 created 1961, deleted 1978)
3.2.1.27: alpha-1,3-glucosidase (EC 3.2.1.27 created 1961, deleted 1972)
3.2.1.29: chitobiase. Now included with EC 3.2.1.52 beta-L-N-acetylhexosaminidase (EC 3.2.1.29 created 1961, deleted 1972)
3.2.1.30: beta-D-acetylglucosaminidase. Now included with EC 3.2.1.52 beta-L-N-acetylhexosaminidase (EC 3.2.1.30 created 1961, deleted 1992)
3.2.1.34: chondroitinase. Now included with EC 3.2.1.35 hyalurononglucosaminidase (EC 3.2.1.34 created 1965, deleted 1972)
3.2.1.69: amylopectin 6-glucanohydrolase. Now included with EC 3.2.1.41 pullulanase (EC 3.2.1.69 created 1972, deleted 1976)
3.2.1.79: alpha-L-arabinofuranoside hydrolase. Now included with EC 3.2.1.55 alpha-N-arabinofuranosidase (EC 3.2.1.79 created 1972, deleted 1976)
3.2.1.90: arabinogalactan endo-1,3-beta-galactosidase not sufficiently characterised. (EC 3.2.1.90 created 1976, deleted 2001)
3.2.1.148: ribosylhomocysteinase. The activity is most probably attributable to EC 4.4.1.21 S-ribosylhomocysteine lyase (EC 3.2.1.148 created 1972 as EC 3.3.1.3, transferred 2001 to EC 3.2.1.148, transferred 2004 to EC 3.13.1.2, deleted 2005)
3.2.1.160: xyloglucan-specific exo-beta-1,4-glucanase. The enzyme was shown to be identical to EC 3.2.1.155, xyloglucan-specific exo-beta-1,4-glucanase, during the public-review process so was withdrawn before being made official. (EC 3.2.1.160 created 2006, deleted 2006)
3.2.2.18: glycopeptide N-glycosidase. Now included with EC 3.5.1.52 N4-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.2.2.18 created 1984, deleted 1989)
3.4.11.11: aminopeptidase (EC 3.4.11.11 created 1978, deleted 1992)
3.4.11.12: thermophilic aminopeptidase (EC 3.4.11.12 created 1978, deleted 1997)
3.4.13.14: gamma-glutamyldipeptidase (EC 3.4.13.14 created 1989, deleted 1992)
3.4.13.16: aspartylphenylalanine dipeptidase (EC 3.4.13.16 created 1989, deleted 1992)
3.4.14.7: tetralysine endopeptidase (EC 3.4.14.7 created 1989, deleted 1992)
3.4.17.5: aspartate carboxypeptidase [EC 3.4.17.5 created 1972 as EC 3.4.12.9, transferred 1978 to EC 3.4.17.5, deleted 1992]
3.4.19.4: N-Acetylmethionylpeptide peptidase (EC 3.4.19.4 created 1989, deleted 1992)
3.4.21.16: Alternaria serine proteinase (EC 3.4.21.16 created 1972, deleted 1992)
3.4.21.17: Arthrobacter serine proteinase (EC 3.4.21.17 created 1972, deleted 1978 [transferred to EC 3.4.21.14, deleted 1992])
3.4.21.18: Tenebrio alpha-proteinase (EC 3.4.21.18 created 1972 [EC 3.4.99.24 created 1972, incorporated 1978], deleted 1992)
3.4.21.23: Vipera russelli proteinase (EC 3.4.21.23 created 1978, deleted 1992)
3.4.21.24: red cell neutral endopeptidase (EC 3.4.21.24 created 1978, deleted 1992)
3.4.21.33: Entomophthora collagenolytic proteinase (EC 3.4.21.33 created 1978, deleted 1992)
3.4.21.40: submandibular proteinase A (EC 3.4.21.40 created 1981, deleted 1992)
3.4.21.51: Leukocyte-membrane neutral endopeptidase (EC 3.4.21.51 created 1984, deleted 1992)
3.4.21.52: Cathepsin R (EC 3.4.21.52 created 1981 as EC 3.4.99.33, transferred 1984 to EC 3.4.21.52, deleted 1992)
3.4.21.56: Euphorbain (EC 3.4.21.56 created 1972 as EC 3.4.99.7, transferred 1989 to EC 3.4.21.56, deleted 1992)
3.4.21.58: prohormone serine proteinase (EC 3.4.21.58 created 1989, deleted 1992)
3.4.22.13: staphylococcal cysteine proteinase (EC 3.4.22.13 created 1978, modified 1981, deleted 1992)
3.4.22.20: dinorphin-converting enzyme (EC 3.4.22.20 created 1989, deleted 1992)
3.4.23.11: thyroid aspartic proteinase (EC 3.4.23.11 created 1978, modified 1981, deleted 1992)
3.4.23.13: Lotus aspartic proteinase (EC 3.4.23.13 created 1978, modified 1981, deleted 1992)
3.4.23.14: sorghum aspartic proteinase (EC 3.4.23.14 created 1978, modified 1981, deleted 1992)
3.4.24.2: Sepia proteinase (EC 3.4.24.2 created 1972, deleted 1992)
3.4.24.5: lens neutral proteinase. Now included with EC 3.4.22.17 - calpain and EC 3.4.99.46 - multicatalytic endopeptidase complex (EC 3.4.24.5 created 1978, deleted 1989)
3.4.24.9: Trichophyton schoenleinii collagenase (EC 3.4.24.9 created 1978, deleted 1992)
3.4.24.10: Trichophyton mentagrophytes keratinase (EC 3.4.24.10 created 1972 as EC 3.4.99.12, transferred 1978 to EC 3.4.24.10, deleted 1992)
3.4.99.2: agavain (EC 3.4.99.2 created 1972, deleted 1992)
3.4.99.3: angiotensinase (EC 3.4.99.3 created 1972, deleted 1992)
3.4.99.7: euphorbain (EC 3.4.99.7 created 1972, deleted 1989)
3.4.99.8: Gliocladium proteinase (EC 3.4.99.8 created 1972, deleted 1992)
3.4.99.9: hurain (EC 3.4.99.9 created 1972, deleted 1992)
3.4.99.11: streptomyces alkalophilic keratinase (EC 3.4.99.11 created 1965 as EC 3.4.4.25, transferred 1972 to EC 3.4.99.11, deleted 1992)
3.4.99.12: trichophyton mentagrophytes keratinase (EC 3.4.99.12 created 1972, deleted 1978 [transferred to EC 3.4.24.10, deleted 1992])
3.4.99.14: mexicanain (EC 3.4.99.14 created 1972, deleted 1992)
3.4.99.15: paecilomyces proteinase (EC 3.4.99.15 created 1972, deleted 1978 [transferred to EC 3.4.23.6, deleted 1992])
3.4.99.16: penicillium notatum extracellular proteinase (EC 3.4.99.16 created 1972, deleted 1992)
3.4.99.17: peptidoglycan endopeptidase (EC 3.4.99.17 created 1972, deleted 1992)
3.4.99.18: pinguinain (EC 3.4.99.18 created 1972, deleted 1992)
3.4.99.20: scopulariopsis proteinase (EC 3.4.99.20 created 1972, deleted 1992)
3.4.99.21: solanain (EC 3.4.99.21 created 1972, deleted 1992)
3.4.99.23: tabernamontanain (EC 3.4.99.23 created 1972, deleted 1992)
3.4.99.24: Tenebrio alpha-proteinase (EC 3.4.99.24 created 1972, deleted 1978 [transferred to EC 3.4.21.18, deleted 1992])
3.4.99.27: Echis carinatus prothrombin-activating proteinase (EC 3.4.99.27 created 1978, deleted 1992)
3.4.99.29: myxobacter AL-1 proteinase I (EC 3.4.99.29 created 1978, deleted 1992)
3.4.99.33: cathepsin R (EC 3.4.99.33 created 1981, deleted 1984 [transferred to EC 3.4.21.52, deleted 1992])
3.4.99.34: mytilidase (EC 3.4.99.34 created 1981, deleted 1992)
3.4.99.37: RecA peptidase (EC 3.4.99.37 created 1989, deleted 1992)
3.4.99.39: pseudomurein endopeptidase (EC 3.4.99.39 created 1989, deleted 1992)
3.4.99.40: Pro-gonadoliberin proteinase (EC 3.4.99.40 created 1989, deleted 1992)
3.4.99.42: leucyllysine endopeptidase (EC 3.4.99.42 created 1990, deleted 1992)
3.5.1.34: acetylhistidine deacetylase. Identical with EC 3.4.13.5 X-methyl-His dipeptidase (EC 3.5.1.34 created 1972, deleted 1981)
3.5.1.37: 4-L-aspartylglycosylamine amidohydrolase. Identical with EC 3.5.1.26 N4-(beta-N-acetylglucosaminyl)-L-asparaginase (EC 3.5.1.37 created 1972, deleted 1976)
3.5.1.45: urease (ATP-hydrolysing). Now listed only as EC 6.3.4.6 urea carboxylase (EC 3.5.1.45 created 1978, deleted 1986)
3.5.1.80: identical to EC 3.5.1.25, N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.80 created 1999, deleted 2002)
3.5.2.8: cephalosporinase. Now included with EC 3.5.2.6 beta-lactamase (EC 3.5.2.8 created 1972, deleted 1978)
3.6.1.4: adenosinetriphosphatase (Mg-activated). Now included with EC 3.6.1.3 adenosinetriphosphatase (EC 3.6.1.4 created 1961, deleted 1965)
3.6.3.13: identical to EC 3.6.3.1 (EC 3.6.3.13 created 2000, deleted 2001)
3.6.3.45: steroid-transporting ATPase. Now included with EC 3.6.3.44, xenobiotic-transporting ATPase (EC 3.6.3.45 created 2000, deleted 2006)
3.13.1.2: 5-deoxyribos-5-ylhomocysteinase. The activity is most probably attributable to EC 4.4.1.21, S-ribosylhomocysteine lyase. (EC 3.13.1.2 created 1972 as EC 3.3.1.3, transferred 2001 to EC 3.2.1.148, transferred 2004 to EC 3.13.1.2, deleted 2005)
4.1.1.10: formerly aminomalonate decarboxylase. Now included with EC 4.1.1.12 aspartate 4-decarboxylase (EC 4.1.1.10 created 1961, deleted 1972)
4.1.1.13: carbamoylaspartate decarboxylase (EC 4.1.1.13 created 1961, deleted 1972)
4.1.1.26: DOPA decarboxylase. Now included with EC 4.1.1.28 aromatic-L-amino-acid decarboxylase (EC 4.1.1.26 created 1961, deleted 1972)
4.1.1.27: tryptophan decarboxylase. Now included with EC 4.1.1.28 aromatic-L-amino-acid decarboxylase (EC 4.1.1.27 created 1961, deleted 1972)
4.1.2.1: hydroxyoxobutyrate aldolase. Now included with EC 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.2.1 created 1961, deleted 1972)
4.1.2.3: pentosealdolase (EC 4.1.2.3 created 1961, deleted 1972)
4.1.2.6: allothreonine aldolase. Reaction is due to EC 2.1.2.1 glycine hydroxymethyltransferase) (EC 4.1.2.6 created 1961, deleted 1972)
4.1.2.7: ketose-1-phosphate aldolase. Now included with EC 4.1.2.13 fructose-bisphosphate aldolase (EC 4.1.2.7 created 1961, deleted 1972)
4.1.2.31: 2-oxo-4-hydroxyglutarate aldolase. Now included with EC 4.1.3.16 4-hydroxy-2-oxoglutarate aldolase (EC 4.1.2.31 created 1978, deleted 1982)
4.2.1.15: homoserine dehydratase. Identical with EC 4.4.1.1 cystathionine gamma-lyase (EC 4.2.1.15 created 1961, deleted 1972)
4.2.1.21: cystathionine beta-synthase. Now EC 4.2.1.22 cystathionine beta-synthase (EC 4.2.1.21 created 1961, deleted 1964)
4.2.1.23: methylcysteine synthase. The reaction was due to a side-reaction of EC 4.2.1.22 cystathionine beta-synthase (EC 4.2.1.23 created 1961, deleted 1972)
4.2.1.71: acetylenecarboxylate hydratase. This enzyme is identical to EC 4.2.1.27, acetylenecarboxylate hydratase (EC 4.2.1.71 created 1978, modified 1989, modified 2000, deleted 2004)
4.2.1.86: 16-dehydroprogesterone hydratase (reaction is identical to that of EC 4.2.1.98, 16alpha-hydroxyprogesterone dehydratase) (EC 4.2.1.86 created 1989, deleted 2004)
4.2.99.5: polyglucuronide lyase (EC 4.2.99.5 created 1965, deleted 1972)
4.2.99.6: chondroitin sulfate lyase. Now included with EC 4.2.2.4 (chondroitin ABC lyase) and EC 4.2.2.5 (chondroitin AC lyase) (EC 4.2.99.6 created 1965, deleted 1972)
4.2.99.17: listed as EC 4.2.99.14 beta-pyrazolylalanine synthase (acetylserine) (EC 4.2.99.17 created 1992, deleted 1992)
4.3.1.21: aminodeoxygluconate ammonia-lyase. Enzyme is identical to EC 4.3.1.9, glucosaminate ammonia-lyase (EC 4.3.1.21 created 1965 as EC 4.2.1.26, transferred 2002 to EC 4.3.1.21, deleted 2004)
4.4.1.7: S-(hydroxyalkyl)glutathione lyase. Now included with EC 2.5.1.18 glutathione transferase (EC 4.4.1.7 created 1972, deleted 1976)
4.4.1.12: sulfoacetaldehyde lyase. Activity due to EC 2.3.3.15, sulfoacetaldehyde acetyltransferase. (EC 4.4.1.12 created 1976, deleted 2003)
5.2.1.11: 4-hydroxyphenylacetaldehyde-oxime isomerase. The existence of this enzyme has been called into question by one of the authors of the reference cited (EC 5.2.1.11 created 1992, deleted 2005)
5.3.1.2: erythrose isomerase (EC 5.3.1.2 created 1961, deleted 1976)
5.3.1.11: acetylglucosaminephosphate isomerase (EC 5.3.1.11 created 1961, deleted 1978)
5.3.1.18: glucose isomerase. Reaction is due to EC 5.3.1.9 glucose-6-phosphate isomerase, in the presence of arsenate, or EC 5.3.1.5 xylose isomerase (EC 5.3.1.18 created 1972, deleted 1978)
5.3.99.1: hydroperoxide isomerase. Reaction due to combined action of EC 4.2.1.92 (hydroperoxide dehydratase) and EC 5.3.99.6 (allene-oxide cyclase) (EC 5.3.99.1 created 1972, deleted 1992)
5.4.3.1: ornithine 4,5-aminomutase. This reaction was due to a mixture of EC 5.1.1.12 (ornithine racemase) and EC 5.4.3.5 (D-ornithine 4,5-aminomutase) (EC 5.4.3.1 created 1972, deleted 1976)
5.4.99.10: Now included with EC 5.4.99.11 isomaltulose synthase (EC 5.4.99.10 created 1984, deleted 1992)
6.1.1.8: D-alanine-sRNA synthetase (created 1961, deleted 1965)
6.2.1.21: phenylacetate-CoA ligase. Activity covered by EC 6.2.1.30, phenylacetate—CoA ligase (EC 6.2.1.21 created 1986, deleted 2001)
6.2.1.29: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanate—CoA ligase. The enzyme is identical to EC 6.2.1.7, cholate—CoA ligase (EC 6.2.1.29 created 1992, deleted 2005)
6.3.2.15: UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase. The activity observed is due to EC 6.3.2.10, UDP-N-acetylmuramoyl-tripeptide—D-alanyl-D-alanine ligase. (EC 6.3.2.15 created 1976, deleted 2002)